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Aminophosphinates against Helicobacter pylori ureolysis—Biochemical and whole-cell inhibition characteristics
Urease is an important virulence factor from Helicobacter pylori that enables bacterial colonization of human gastric mucosa. Specific inhibition of urease activity can be regarded as a promising adjuvant strategy for eradication of this pathogen. A group of organophosphorus inhibitors of urease, na...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550016/ https://www.ncbi.nlm.nih.gov/pubmed/28792967 http://dx.doi.org/10.1371/journal.pone.0182437 |