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Aminophosphinates against Helicobacter pylori ureolysis—Biochemical and whole-cell inhibition characteristics

Urease is an important virulence factor from Helicobacter pylori that enables bacterial colonization of human gastric mucosa. Specific inhibition of urease activity can be regarded as a promising adjuvant strategy for eradication of this pathogen. A group of organophosphorus inhibitors of urease, na...

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Detalles Bibliográficos
Autores principales: Macegoniuk, Katarzyna, Grela, Ewa, Biernat, Monika, Psurski, Mateusz, Gościniak, Grażyna, Dziełak, Anna, Mucha, Artur, Wietrzyk, Joanna, Berlicki, Łukasz, Grabowiecka, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550016/
https://www.ncbi.nlm.nih.gov/pubmed/28792967
http://dx.doi.org/10.1371/journal.pone.0182437