Cargando…

Structural basis for high-affinity fluorophore binding and activation by RNA Mango

Genetically encoded fluorescent protein tags revolutionized proteome studies, while the lack of intrinsically fluorescent RNAs has hindered transcriptome exploration. Among several RNA-fluorophore complexes that potentially address this problem, RNA Mango has an exceptionally high affinity for its t...

Descripción completa

Detalles Bibliográficos
Autores principales: Trachman, Robert J., Demeshkina, Natalia A., Lau, Matthew W.L., Panchapakesan, Shanker Shyam S., Jeng, Sunny C.Y., Unrau, Peter J., Ferré-D’Amaré, Adrian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550021/
https://www.ncbi.nlm.nih.gov/pubmed/28553947
http://dx.doi.org/10.1038/nchembio.2392