Downregulation of LGR5 Expression Inhibits Cardiomyocyte Differentiation and Potentiates Endothelial Differentiation from Human Pluripotent Stem Cells

Understanding molecules involved in differentiation of human pluripotent stem cells (hPSCs) into cardiomyocytes and endothelial cells is important in advancing hPSCs for cell therapy and drug testing. Here, we report that LGR5, a leucine-rich repeat-containing G-protein-coupled receptor, plays a cri...

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Detalles Bibliográficos
Autores principales: Jha, Rajneesh, Singh, Monalisa, Wu, Qingling, Gentillon, Cinsley, Preininger, Marcela K., Xu, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550222/
https://www.ncbi.nlm.nih.gov/pubmed/28793247
http://dx.doi.org/10.1016/j.stemcr.2017.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550222/
https://www.ncbi.nlm.nih.gov/pubmed/28793247
http://dx.doi.org/10.1016/j.stemcr.2017.07.006

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