Cargando…

Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells

Renal cell carcinoma (RCC) is a deadly malignancy due to its tendency to metastasize and resistance to chemotherapy. Stem-like tumor cells often confer these aggressive behaviors. We discovered an endoglin (CD105)-expressing subpopulation in human RCC xenografts and patient samples with a greater ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Junhui, Guan, Wei, Liu, Peijun, Dai, Jin, Tang, Kun, Xiao, Haibing, Qian, Yuan, Sharrow, Allison C., Ye, Zhangqun, Wu, Lily, Xu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550272/
https://www.ncbi.nlm.nih.gov/pubmed/28793246
http://dx.doi.org/10.1016/j.stemcr.2017.07.009