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Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells

Renal cell carcinoma (RCC) is a deadly malignancy due to its tendency to metastasize and resistance to chemotherapy. Stem-like tumor cells often confer these aggressive behaviors. We discovered an endoglin (CD105)-expressing subpopulation in human RCC xenografts and patient samples with a greater ca...

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Detalles Bibliográficos
Autores principales:	Hu, Junhui, Guan, Wei, Liu, Peijun, Dai, Jin, Tang, Kun, Xiao, Haibing, Qian, Yuan, Sharrow, Allison C., Ye, Zhangqun, Wu, Lily, Xu, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550272/ https://www.ncbi.nlm.nih.gov/pubmed/28793246 http://dx.doi.org/10.1016/j.stemcr.2017.07.009

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