Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells

Formation of blood vessels, or angiogenesis, is crucial to cancer progression. Thus, inhibiting angiogenesis can limit the growth and spread of tumors. The natural polyphenol catechin has moderate anti-tumor activity and interacts with copper, which is essential for angiogenesis. Catechin is easily...

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Detalles Bibliográficos
Autores principales: Yee, Eugene M. H., Brandl, Miriam B., Pasquier, Eddy, Cirillo, Giuseppe, Kimpton, Kathleen, Kavallaris, Maria, Kumar, Naresh, Vittorio, Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550437/
https://www.ncbi.nlm.nih.gov/pubmed/28794411
http://dx.doi.org/10.1038/s41598-017-07452-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550437/
https://www.ncbi.nlm.nih.gov/pubmed/28794411
http://dx.doi.org/10.1038/s41598-017-07452-w

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