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Neonatal leptin treatment reverses the bone-suppressive effects of maternal undernutrition in adult rat offspring

Alterations in the early life environment, including maternal undernutrition (UN) during pregnancy, can lead to increased risk of metabolic and cardiovascular disorders in offspring. Leptin treatment of neonates born to UN rats reverses the programmed metabolic phenotype, but the possible benefits o...

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Detalles Bibliográficos
Autores principales: Firth, Elwyn C., Gamble, Greg D., Cornish, Jillian, Vickers, Mark H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550441/
https://www.ncbi.nlm.nih.gov/pubmed/28794412
http://dx.doi.org/10.1038/s41598-017-07500-5