Measuring inter-protein pairwise interaction energies from a single native mass spectrum by double-mutant cycle analysis

The strength and specificity of protein complex formation is crucial for most life processes and is determined by interactions between residues in the binding partners. Double-mutant cycle analysis provides a strategy for studying the energetic coupling between amino acids at the interfaces of such...

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Detalles Bibliográficos
Autores principales: Sokolovski, Miri, Cveticanin, Jelena, Hayoun, Déborah, Korobko, Ilia, Sharon, Michal, Horovitz, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550451/
https://www.ncbi.nlm.nih.gov/pubmed/28794496
http://dx.doi.org/10.1038/s41467-017-00285-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550451/
https://www.ncbi.nlm.nih.gov/pubmed/28794496
http://dx.doi.org/10.1038/s41467-017-00285-1

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