Vitamin B(12) as a carrier of peptide nucleic acid (PNA) into bacterial cells

Short modified oligonucleotides targeted at bacterial DNA or RNA could serve as antibacterial agents provided that they are efficiently taken up by bacterial cells. However, the uptake of such oligonucleotides is hindered by the bacterial cell wall. To overcome this problem, oligomers have been atta...

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Detalles Bibliográficos
Autores principales: Równicki, Marcin, Wojciechowska, Monika, Wierzba, Aleksandra J., Czarnecki, Jakub, Bartosik, Dariusz, Gryko, Dorota, Trylska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550456/
https://www.ncbi.nlm.nih.gov/pubmed/28794451
http://dx.doi.org/10.1038/s41598-017-08032-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550456/
https://www.ncbi.nlm.nih.gov/pubmed/28794451
http://dx.doi.org/10.1038/s41598-017-08032-8

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