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Vitamin B(12) as a carrier of peptide nucleic acid (PNA) into bacterial cells
Short modified oligonucleotides targeted at bacterial DNA or RNA could serve as antibacterial agents provided that they are efficiently taken up by bacterial cells. However, the uptake of such oligonucleotides is hindered by the bacterial cell wall. To overcome this problem, oligomers have been atta...
Autores principales: | Równicki, Marcin, Wojciechowska, Monika, Wierzba, Aleksandra J., Czarnecki, Jakub, Bartosik, Dariusz, Gryko, Dorota, Trylska, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550456/ https://www.ncbi.nlm.nih.gov/pubmed/28794451 http://dx.doi.org/10.1038/s41598-017-08032-8 |
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