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Ebola virus VP24 interacts with NP to facilitate nucleocapsid assembly and genome packaging

Ebola virus causes devastating hemorrhagic fever outbreaks for which no approved therapeutic exists. The viral nucleocapsid, which is minimally composed of the proteins NP, VP35, and VP24, represents an attractive target for drug development; however, the molecular determinants that govern the inter...

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Detalles Bibliográficos
Autores principales: Banadyga, Logan, Hoenen, Thomas, Ambroggio, Xavier, Dunham, Eric, Groseth, Allison, Ebihara, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550494/
https://www.ncbi.nlm.nih.gov/pubmed/28794491
http://dx.doi.org/10.1038/s41598-017-08167-8