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Progression of Tubulointerstitial Fibrosis and the Chronic Kidney Disease Phenotype – Role of Risk Factors and Epigenetics

Although the kidney has capacity to repair after mild injury, ongoing or severe damage results in scarring (fibrosis) and an associated progressive loss of kidney function. However, despite its universal significance, evidence highlights a population based heterogeneity in the trajectory of chronic...

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Detalles Bibliográficos
Autores principales: Hewitson, Timothy D., Holt, Stephen G., Smith, Edward R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550676/
https://www.ncbi.nlm.nih.gov/pubmed/28848437
http://dx.doi.org/10.3389/fphar.2017.00520