The Generation of Mouse and Human Huntington Disease iPS Cells Suitable for In vitro Studies on Huntingtin Function

Huntington disease (HD) is an incurable neurodegenerative disorder caused by expansion of CAG repeats in huntingtin (HTT) gene, resulting in expanded polyglutamine tract in HTT protein. Although, HD has its common onset in adulthood, subtle symptoms in patients may occur decades before diagnosis, an...

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Detalles Bibliográficos
Autores principales: Szlachcic, Wojciech J., Wiatr, Kalina, Trzeciak, Marta, Figlerowicz, Marek, Figiel, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550714/
https://www.ncbi.nlm.nih.gov/pubmed/28848389
http://dx.doi.org/10.3389/fnmol.2017.00253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550714/
https://www.ncbi.nlm.nih.gov/pubmed/28848389
http://dx.doi.org/10.3389/fnmol.2017.00253

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