Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile Virulence

Clostridium difficile is a spore-forming anaerobic bacterium that causes colitis in patients with disrupted colonic microbiota. While some individuals are asymptomatic C. difficile carriers, symptomatic disease ranges from mild diarrhea to potentially lethal toxic megacolon. The wide disease spectru...

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Detalles Bibliográficos
Autores principales: Lewis, Brittany B., Carter, Rebecca A., Ling, Lilan, Leiner, Ingrid, Taur, Ying, Kamboj, Mini, Dubberke, Erik R., Xavier, Joao, Pamer, Eric G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550754/
https://www.ncbi.nlm.nih.gov/pubmed/28790208
http://dx.doi.org/10.1128/mBio.00885-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550754/
https://www.ncbi.nlm.nih.gov/pubmed/28790208
http://dx.doi.org/10.1128/mBio.00885-17

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