Cargando…

Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile Virulence

Clostridium difficile is a spore-forming anaerobic bacterium that causes colitis in patients with disrupted colonic microbiota. While some individuals are asymptomatic C. difficile carriers, symptomatic disease ranges from mild diarrhea to potentially lethal toxic megacolon. The wide disease spectru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lewis, Brittany B., Carter, Rebecca A., Ling, Lilan, Leiner, Ingrid, Taur, Ying, Kamboj, Mini, Dubberke, Erik R., Xavier, Joao, Pamer, Eric G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550754/ https://www.ncbi.nlm.nih.gov/pubmed/28790208 http://dx.doi.org/10.1128/mBio.00885-17

Ejemplares similares

Accessory Gene Regulator-1 Locus Is Essential for Virulence and Pathogenesis of Clostridium difficile
por: Darkoh, Charles, et al.
Publicado: (2016)

Erratum for Darkoh et al., “Accessory Gene Regulator-1 Locus Is Essential for Virulence and Pathogenesis of Clostridium difficile”
por: Darkoh, Charles, et al.
Publicado: (2017)

The agr Locus Regulates Virulence and Colonization Genes in Clostridium difficile 027
por: Martin, Melissa J., et al.
Publicado: (2013)

Precision microbiome restoration of bile acid-mediated resistance to Clostridium difficile
por: Buffie, Charlie G., et al.
Publicado: (2014)

Burden of Clostridium difficile on the Healthcare System
por: Dubberke, Erik R., et al.
Publicado: (2012)

Evolutionary History of the Clostridium difficile Pathogenicity Locus
por: Dingle, Kate E., et al.
Publicado: (2013)

Etiology of Infectious Diarrhea in Patients Tested for Clostridium difficile: If It Isn’t Clostridium difficile, What Is It?
por: Kwon, Jennie H, et al.
Publicado: (2017)

Toxin B is essential for virulence of Clostridium difficile
por: Lyras, Dena, et al.
Publicado: (2009)

Early Clostridium difficile Infection during Allogeneic Hematopoietic Stem Cell Transplantation
por: Kinnebrew, Melissa A., et al.
Publicado: (2014)

Clinical Clostridium difficile: Clonality and Pathogenicity Locus Diversity
por: Dingle, Kate E., et al.
Publicado: (2011)

The Complexity and Diversity of the Pathogenicity Locus in Clostridium difficile Clade 5
por: Elliott, Briony, et al.
Publicado: (2014)

Pleiotropic roles of Clostridium difficile sin locus
por: Girinathan, Brintha Parasumanna, et al.
Publicado: (2018)

2390. Acquisition of Clostridium difficile Infection Following Exposure from Roommate Defined by Concordance on Genotyping
por: Aslam, Anoshé, et al.
Publicado: (2019)

504. Change in Clostridium difficile Strain-Type Distribution After Implementation of Diagnostic Stewardship
por: McMillen, Tracy, et al.
Publicado: (2018)

A Clostridium difficile Cell Wall Glycopolymer Locus Influences Bacterial Shape, Polysaccharide Production and Virulence
por: Chu, Michele, et al.
Publicado: (2016)

Clostridium difficile: New Insights into the Evolution of the Pathogenicity Locus
por: Monot, Marc, et al.
Publicado: (2015)

Phase variation of Clostridium difficile virulence factors
por: Anjuwon-Foster, Brandon R., et al.
Publicado: (2017)

ICD-9 Codes and Surveillance for Clostridium difficile–associated Disease
por: Dubberke, Erik R., et al.
Publicado: (2006)

Dietary trehalose enhances virulence of epidemic Clostridium difficile
por: Collins, J., et al.
Publicado: (2018)

Enhanced Cleaning and Education to Prevent Transmission of Clostridium difficile in Pediatrics
por: Aslam, Anoshé, et al.
Publicado: (2017)

Commensal microbes provide first line defense against Listeria monocytogenes infection
por: Becattini, Simone, et al.
Publicado: (2017)

Quantifying Transmission of Clostridium difficile within and outside Healthcare Settings
por: Durham, David P., et al.
Publicado: (2016)

Epidemiology of Clostridium difficile infection Among Patients with Newly Diagnosed or Relapsed Acute Leukemia: A Single-center Experience
por: Garcia, Alexandra Franco, et al.
Publicado: (2017)

535. Transmission of Clostridium difficile (CD) From Patients ≤2 Years of Age in a Pediatric Oncology Setting
por: Robilotti, Elizabeth, et al.
Publicado: (2018)

Increasing Age Has Limited Impact on Risk of Clostridium difficile Infection in an Elderly Population
por: Olsen, Margaret A, et al.
Publicado: (2018)

Emergence of an Outbreak-Associated Clostridium difficile Variant with Increased Virulence
por: Quesada-Gómez, Carlos, et al.
Publicado: (2015)

Virulence Factors of Clostridioides (Clostridium) difficile Linked to Recurrent Infections
por: Tijerina-Rodríguez, Laura, et al.
Publicado: (2019)

Genotypic Correlation between Cases of Clostridium difficile (CDI) with Community-Onset Diagnosis after Recent Hospital Discharge and Their Prior Unit-Based Contacts
por: Aslam, Anoshé, et al.
Publicado: (2017)

A multisite genomic epidemiology study of Clostridioides difficile infections in the USA supports differential roles of healthcare versus community spread for two common strains
por: Miles-Jay, Arianna, et al.
Publicado: (2021)

Core-, pan- and accessory genome analyses of Clostridium neonatale: insights into genetic diversity
por: Mesa, Victoria, et al.
Publicado: (2022)

Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile
por: Dong, Qiwen, et al.
Publicado: (2023)

Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile
por: Dong, Qiwen, et al.
Publicado: (2023)

Attributable Outcomes of Endemic Clostridium difficile–associated Disease in Nonsurgical Patients
por: Dubberke, Erik R., et al.
Publicado: (2008)

Different molecular characteristics and antimicrobial resistance profiles of Clostridium difficile in the Asia-Pacific region
por: Luo, Yun, et al.
Publicado: (2019)

Epidemiological and economic burden of Clostridium difficile in the United States: estimates from a modeling approach
por: Desai, Kamal, et al.
Publicado: (2016)

Hash-Based Core Genome Multilocus Sequence Typing for Clostridium difficile
por: Eyre, David W., et al.
Publicado: (2019)

Genome Resequencing of the Virulent and Multidrug-Resistant Reference Strain Clostridium difficile 630
por: Riedel, Thomas, et al.
Publicado: (2015)

Evaluation of the Xpert Clostridium difficile Assay for the Diagnosis of Clostridium difficile Infection
por: Shin, Saeam, et al.
Publicado: (2012)

The burden of clostridium difficile infection: estimates of the incidence of CDI from U.S. Administrative databases
por: Olsen, Margaret A., et al.
Publicado: (2016)

2322: The effects of fecal microbiota transplantation on the gut microbiota in subjects with Clostridium difficile infection
por: Elizabeth Langdon, Amy, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1qg2ovpg7s4apmeuve8dnclgn7