Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy

Hepatocellular carcinoma (HCC) is one of the most lethal and prevalent cancers worldwide. CD147 (EMMPRIN or basigin) is a leading gene relating to hepatocarcinogenesis and metastasis, and is detected in transmembrane, exosome or circulating forms in HCC patients. The endosome recycling of CD147 furt...

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Detalles Bibliográficos
Autores principales: Wu, Bo, Cui, Jian, Yang, Xiang-Min, Liu, Zhen-Yu, Song, Fei, Li, Ling, Jiang, Jian-Li, Chen, Zhi-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550841/
https://www.ncbi.nlm.nih.gov/pubmed/28703811
http://dx.doi.org/10.1038/cddis.2017.251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550841/
https://www.ncbi.nlm.nih.gov/pubmed/28703811
http://dx.doi.org/10.1038/cddis.2017.251

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