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MICU1 protects against myocardial ischemia/reperfusion injury and its control by the importer receptor Tom70

Mitochondrial Ca(2+) overload is a main contributor to mitochondrial damage hence cardiomyocyte death in myocardial ischemia/reperfusion (MI/R) injury. MICU1 has been recently identified as an important regulator of mitochondrial Ca(2+) homeostasis. Here we try to identify the role of MICU1 in MI/R,...

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Detalles Bibliográficos
Autores principales: Xue, Qiang, Pei, Haifeng, Liu, Qinshe, Zhao, Mingjun, Sun, Jing, Gao, Erhe, Ma, Xinliang, Tao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550843/
https://www.ncbi.nlm.nih.gov/pubmed/28703803
http://dx.doi.org/10.1038/cddis.2017.280