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Interleukin-22 ameliorated renal injury and fibrosis in diabetic nephropathy through inhibition of NLRP3 inflammasome activation

Diabetic nephropathy (DN) is one of the most lethal complications of diabetes mellitus with metabolic disorders and chronic inflammation. Although the cytokine IL-22 was initially implicated in the pathogenesis of chronic inflammatory diseases, recent studies suggested that IL-22 could suppress infl...

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Detalles Bibliográficos
Autores principales: Wang, Shaofei, Li, Yubin, Fan, Jiajun, Zhang, Xuyao, Luan, Jingyun, Bian, Qi, Ding, Tao, Wang, Yichen, Wang, Ziyu, Song, Ping, Cui, Daxiang, Mei, Xiaobin, Ju, Dianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550847/
https://www.ncbi.nlm.nih.gov/pubmed/28726774
http://dx.doi.org/10.1038/cddis.2017.292