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Pre-synaptic TrkB in basolateral amygdala neurons mediates BDNF signaling transmission in memory extinction

Brain-derived neurotrophic factor (BDNF) and its high affinity receptor, TrkB, play an essential role in memory extinction. Our previous work has shown that JIP3 (JNK interacted protein 3) mediates anterograde axonal transport of TrkB through the direct binding of its coiled-coil domain 1 (CC1) with...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Wang, Dongdong, Li, Yang, Chu, Hongxia, Zhang, Lining, Hou, Ming, Jiang, Xingyu, Chen, Zheyu, Su, Bo, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550851/
https://www.ncbi.nlm.nih.gov/pubmed/28749471
http://dx.doi.org/10.1038/cddis.2017.302