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p75(NTR) antagonists attenuate photoreceptor cell loss in murine models of retinitis pigmentosa

ProNGF signaling through p75(NTR) has been associated with neurodegenerative disorders. Retinitis pigmentosa (RP) comprises a group of inherited retinal dystrophies that causes progressive photoreceptor cell degeneration and death, at a rate dependent on the genetic mutation. There are more than 300...

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Detalles Bibliográficos
Autores principales: Platón-Corchado, María, Barcelona, Pablo F, Jmaeff, Sean, Marchena, Miguel, Hernández-Pinto, Alberto M, Hernández-Sánchez, Catalina, Saragovi, H Uri, de la Rosa, Enrique J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550853/
https://www.ncbi.nlm.nih.gov/pubmed/28703796
http://dx.doi.org/10.1038/cddis.2017.306