Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction

Diabetic retinopathy (DR) is a well-known microvascular complication related to inflammation. Mcc950 is a potent and specific inhibitor of the NLRP3 inflammasome but its influence on DR has not been studied. Thus, we evaluated the anti-inflammatory effects of Mcc950 on high-glucose-induced human ret...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Lv, Xuehua, Hu, Zizhong, Ye, Xiaojian, Zheng, Xinhua, Ding, Yuzhi, Xie, Ping, Liu, Qinghuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550855/
https://www.ncbi.nlm.nih.gov/pubmed/28726778
http://dx.doi.org/10.1038/cddis.2017.308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550855/
https://www.ncbi.nlm.nih.gov/pubmed/28726778
http://dx.doi.org/10.1038/cddis.2017.308

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