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MicroRNA-148a deficiency promotes hepatic lipid metabolism and hepatocarcinogenesis in mice
miRNAs are involved in many physiologic and disease processes by virtue of degrading specific mRNAs or inhibiting their translation. miR-148a has been implicated in the control of tumor growth and cholesterol and triglyceride homeostasis using in vitro or in vivo gene expression- and silencing-based...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550856/ https://www.ncbi.nlm.nih.gov/pubmed/28703810 http://dx.doi.org/10.1038/cddis.2017.309 |