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Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells

The acquisition of epithelial–mesenchymal transition (EMT) and/or existence of a sub-population of cancer stem-like cells (CSC) are associated with malignant behavior and chemoresistance. To identify which factor could promote EMT and CSC formation and uncover the mechanistic role of such factor is...

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Detalles Bibliográficos
Autores principales: Gao, Yuran, Zhang, Zhicheng, Li, Kai, Gong, Liying, Yang, Qingzhu, Huang, Xuemei, Hong, Chengcheng, Ding, Mingfeng, Yang, Huanjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550858/
https://www.ncbi.nlm.nih.gov/pubmed/28703793
http://dx.doi.org/10.1038/cddis.2017.311