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RIP3 attenuates the pancreatic damage induced by deletion of ATG7

Invalidation of pancreatic autophagy entails pancreatic atrophy, endocrine and exocrine insufficiency and pancreatitis. The aim of this study was to investigate whether depletion of Rip3, which is involved in necroptotic signaling, may attenuate the pancreatic atrophy and pancreatitis resulting from...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaodong, Xie, Li, Xia, Leizhou, Bergmann, Frank, Büchler, Markus W, Kroemer, Guido, Hackert, Thilo, Fortunato, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550860/
https://www.ncbi.nlm.nih.gov/pubmed/28703808
http://dx.doi.org/10.1038/cddis.2017.313