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DNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the major subtype of renal cell carcinoma (RCC) that is resistant to conventional radiation and chemotherapy. It is a challenge to explore effective therapeutic targets and drugs for this kind of cancer. Transcription factor Krüppel-like factor 5 (KLF5) exe...

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Detalles Bibliográficos
Autores principales: Fu, Rong-Jie, He, Wei, Wang, Xiao-Bo, Li, Lei, Zhao, Huan-Bin, Liu, Xiao-Ye, Pang, Zhi, Chen, Guo-Qiang, Huang, Lei, Zhao, Ke-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550868/
https://www.ncbi.nlm.nih.gov/pubmed/28749461
http://dx.doi.org/10.1038/cddis.2017.323