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BAG3 promotes stem cell-like phenotype in breast cancer by upregulation of CXCR4 via interaction with its transcript

BAG3 is an evolutionarily conserved co-chaperone expressed at high levels and has a prosurvival role in many tumor types. The current study reported that BAG3 was induced under specific floating culture conditions that enrich breast cancer stem cell (BCSC)-like cells in spheres. Ectopic BAG3 overexp...

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Detalles Bibliográficos
Autores principales: Liu, Bao-Qin, Zhang, Song, Li, Si, An, Ming-Xin, Li, Chao, Yan, Jing, Wang, Jia-Mei, Wang, Hua-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550869/
https://www.ncbi.nlm.nih.gov/pubmed/28703799
http://dx.doi.org/10.1038/cddis.2017.324