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The EGFR/miR-338-3p/EYA2 axis controls breast tumor growth and lung metastasis

Dysregulation of the epidermal growth factor receptor (EGFR) promotes cancer cell growth, invasion and metastasis. However, its relevant downstream effectors are still limited. Here, we show that EGFR promotes breast tumor growth and metastasis by downregulating the tumor suppressor micoRNA-338-3p (...

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Detalles Bibliográficos
Autores principales: Liang, Yingchun, Xu, Xiaojie, Wang, Tao, Li, Ying, You, Wenye, Fu, Jing, Liu, Yang, Jin, Shuai, Ji, Quanbo, Zhao, Wei, Song, Qi, Li, Ling, Hong, Tian, Huang, Junjian, Lyu, Zhaohui, Ye, Qinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550870/
https://www.ncbi.nlm.nih.gov/pubmed/28703807
http://dx.doi.org/10.1038/cddis.2017.325