Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats

Autophagy disruption leads to neuronal damage in hypoxic–ischemic brain injury. Rab7, a member of the Rab GTPase superfamily, has a unique role in the regulation of autophagy. Hypoxic preconditioning (HPC) provides neuroprotection against transient global cerebral ischemia (tGCI). However, the under...

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Detalles Bibliográficos
Autores principales: Zhan, Lixuan, Chen, Siyuan, Li, Kongping, Liang, Donghai, Zhu, Xinyong, Liu, Liu, Lu, Zhiwei, Sun, Weiwen, Xu, En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550874/
https://www.ncbi.nlm.nih.gov/pubmed/28726776
http://dx.doi.org/10.1038/cddis.2017.330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550874/
https://www.ncbi.nlm.nih.gov/pubmed/28726776
http://dx.doi.org/10.1038/cddis.2017.330

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