Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression

Liver cancer is the second cause of death from cancer worldwide, without effective treatment. Traditional chemotherapy for liver cancer has big side effects for patients, whereas targeted drugs, such as sorafenib, commonly have drug resistance. Oroxylin A (OA) is the main bioactive flavonoids of Scu...

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Detalles Bibliográficos
Autores principales: Wei, Libin, Dai, Yuanyuan, Zhou, Yuxin, He, Zihao, Yao, Jingyue, Zhao, Li, Guo, Qinglong, Yang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550876/
https://www.ncbi.nlm.nih.gov/pubmed/28726775
http://dx.doi.org/10.1038/cddis.2017.335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550876/
https://www.ncbi.nlm.nih.gov/pubmed/28726775
http://dx.doi.org/10.1038/cddis.2017.335

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