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Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression
Liver cancer is the second cause of death from cancer worldwide, without effective treatment. Traditional chemotherapy for liver cancer has big side effects for patients, whereas targeted drugs, such as sorafenib, commonly have drug resistance. Oroxylin A (OA) is the main bioactive flavonoids of Scu...
Autores principales: | Wei, Libin, Dai, Yuanyuan, Zhou, Yuxin, He, Zihao, Yao, Jingyue, Zhao, Li, Guo, Qinglong, Yang, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550876/ https://www.ncbi.nlm.nih.gov/pubmed/28726775 http://dx.doi.org/10.1038/cddis.2017.335 |
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