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JUN is important for ocular hypertension-induced retinal ganglion cell degeneration

Ocular hypertension, a major risk factor for glaucoma, is thought to trigger glaucomatous neurodegeneration through injury to retinal ganglion cell (RGC) axons. The molecular signaling pathway leading from ocular hypertension to RGC degeneration, however, is not well defined. JNK signaling, a compon...

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Detalles Bibliográficos
Autores principales: Syc-Mazurek, Stephanie B, Fernandes, Kimberly A, Libby, Richard T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550879/
https://www.ncbi.nlm.nih.gov/pubmed/28726785
http://dx.doi.org/10.1038/cddis.2017.338