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JUN is important for ocular hypertension-induced retinal ganglion cell degeneration
Ocular hypertension, a major risk factor for glaucoma, is thought to trigger glaucomatous neurodegeneration through injury to retinal ganglion cell (RGC) axons. The molecular signaling pathway leading from ocular hypertension to RGC degeneration, however, is not well defined. JNK signaling, a compon...
Autores principales: | Syc-Mazurek, Stephanie B, Fernandes, Kimberly A, Libby, Richard T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550879/ https://www.ncbi.nlm.nih.gov/pubmed/28726785 http://dx.doi.org/10.1038/cddis.2017.338 |
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