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Edaravone suppresses retinal ganglion cell death in a mouse model of normal tension glaucoma

Glaucoma, one of the leading causes of irreversible blindness, is characterized by progressive degeneration of optic nerves and retinal ganglion cells (RGCs). In the mammalian retina, excitatory amino-acid carrier 1 (EAAC1) is expressed in neural cells, including RGCs. Loss of EAAC1 leads to RGC deg...

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Detalles Bibliográficos
Autores principales: Akaiwa, Kei, Namekata, Kazuhiko, Azuchi, Yuriko, Guo, Xiaoli, Kimura, Atsuko, Harada, Chikako, Mitamura, Yoshinori, Harada, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550882/
https://www.ncbi.nlm.nih.gov/pubmed/28703795
http://dx.doi.org/10.1038/cddis.2017.341