The cohesin complex prevents Myc-induced replication stress

The cohesin complex is mutated in cancer and in a number of rare syndromes collectively known as Cohesinopathies. In the latter case, cohesin deficiencies have been linked to transcriptional alterations affecting Myc and its target genes. Here, we set out to understand to what extent the role of coh...

Descripción completa

Detalles Bibliográficos
Autores principales: Rohban, Sara, Cerutti, Aurora, Morelli, Marco J, d'Adda di Fagagna, Fabrizio, Campaner, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550886/
https://www.ncbi.nlm.nih.gov/pubmed/28749464
http://dx.doi.org/10.1038/cddis.2017.345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550886/
https://www.ncbi.nlm.nih.gov/pubmed/28749464
http://dx.doi.org/10.1038/cddis.2017.345

Ejemplares similares