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The cohesin complex prevents Myc-induced replication stress
The cohesin complex is mutated in cancer and in a number of rare syndromes collectively known as Cohesinopathies. In the latter case, cohesin deficiencies have been linked to transcriptional alterations affecting Myc and its target genes. Here, we set out to understand to what extent the role of coh...
Autores principales: | Rohban, Sara, Cerutti, Aurora, Morelli, Marco J, d'Adda di Fagagna, Fabrizio, Campaner, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550886/ https://www.ncbi.nlm.nih.gov/pubmed/28749464 http://dx.doi.org/10.1038/cddis.2017.345 |
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