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BMP-induced reprogramming of the neural retina into retinal pigment epithelium requires Wnt signalling

In vertebrates, the retinal pigment epithelium (RPE) and photoreceptors of the neural retina (NR) comprise a functional unit required for vision. During vertebrate eye development, a conversion of the RPE into NR can be induced by growth factors in vivo at optic cup stages, but the reverse process,...

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Detalles Bibliográficos
Autores principales: Steinfeld, Jörg, Steinfeld, Ichie, Bausch, Alexander, Coronato, Nicola, Hampel, Meggi-Lee, Depner, Heike, Layer, Paul G., Vogel-Höpker, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550904/
https://www.ncbi.nlm.nih.gov/pubmed/28546339
http://dx.doi.org/10.1242/bio.018739