Human TTBK1, TTBK2 and MARK1 kinase toxicity in Drosophila melanogaster is exacerbated by co-expression of human Tau

Tau protein is involved in numerous human neurodegenerative diseases, and Tau hyper-phosphorylation has been linked to Tau aggregation and toxicity. Previous studies have addressed toxicity and phospho-biology of human Tau (hTau) in Drosophila melanogaster. However, hTau transgenes have most often b...

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Detalles Bibliográficos
Autores principales: Fernius, Josefin, Starkenberg, Annika, Pokrzywa, Malgorzata, Thor, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550906/
https://www.ncbi.nlm.nih.gov/pubmed/28711868
http://dx.doi.org/10.1242/bio.022749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550906/
https://www.ncbi.nlm.nih.gov/pubmed/28711868
http://dx.doi.org/10.1242/bio.022749

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