Developmental downregulation of LIS1 expression limits axonal extension and allows axon pruning

The robust axonal growth and regenerative capacities of young neurons decrease substantially with age. This developmental downregulation of axonal growth may facilitate axonal pruning and neural circuit formation but limits functional recovery following nerve damage. While external factors influenci...

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Detalles Bibliográficos
Autores principales: Kumamoto, Kanako, Iguchi, Tokuichi, Ishida, Ryuichi, Uemura, Takuya, Sato, Makoto, Hirotsune, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550919/
https://www.ncbi.nlm.nih.gov/pubmed/28630356
http://dx.doi.org/10.1242/bio.025999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550919/
https://www.ncbi.nlm.nih.gov/pubmed/28630356
http://dx.doi.org/10.1242/bio.025999

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