Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism

BACKGROUND: Statins are a class of therapeutics used to regulate serum cholesterol and reduce the risk of heart disease. Although statins are highly effective in removing cholesterol from the blood, their consumption has been linked to potential adverse effects in some individuals. The most common e...

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Detalles Bibliográficos
Autores principales: Caparrós-Martín, Jose A., Lareu, Ricky R., Ramsay, Joshua P., Peplies, Jörg, Jerry Reen, F., Headlam, Henrietta A., Ward, Natalie C., Croft, Kevin D., Newsholme, Philip, Hughes, Jeffery D., O’Gara, Fergal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550934/
https://www.ncbi.nlm.nih.gov/pubmed/28793934
http://dx.doi.org/10.1186/s40168-017-0312-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550934/
https://www.ncbi.nlm.nih.gov/pubmed/28793934
http://dx.doi.org/10.1186/s40168-017-0312-4

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