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Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism
BACKGROUND: Statins are a class of therapeutics used to regulate serum cholesterol and reduce the risk of heart disease. Although statins are highly effective in removing cholesterol from the blood, their consumption has been linked to potential adverse effects in some individuals. The most common e...
Autores principales: | Caparrós-Martín, Jose A., Lareu, Ricky R., Ramsay, Joshua P., Peplies, Jörg, Jerry Reen, F., Headlam, Henrietta A., Ward, Natalie C., Croft, Kevin D., Newsholme, Philip, Hughes, Jeffery D., O’Gara, Fergal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550934/ https://www.ncbi.nlm.nih.gov/pubmed/28793934 http://dx.doi.org/10.1186/s40168-017-0312-4 |
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