Cathepsin-S degraded decorin are elevated in fibrotic lung disorders – development and biological validation of a new serum biomarker

BACKGROUND: Decorin is one of the most abundant proteoglycans of the extracellular matrix and is mainly secreted and deposited in the interstitial matrix by fibroblasts where it plays an important role in collagen turnover and tissue homeostasis. Degradation of decorin might disturb normal tissue ho...

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Detalles Bibliográficos
Autores principales: Kehlet, S.N., Bager, C.L., Willumsen, N., Dasgupta, B., Brodmerkel, C., Curran, M., Brix, S., Leeming, D.J., Karsdal, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550991/
https://www.ncbi.nlm.nih.gov/pubmed/28793886
http://dx.doi.org/10.1186/s12890-017-0455-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550991/
https://www.ncbi.nlm.nih.gov/pubmed/28793886
http://dx.doi.org/10.1186/s12890-017-0455-x

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