RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling

Endogenous satiety hormones provide an attractive target for obesity drugs. Glucagon causes weight loss by reducing food intake and increasing energy expenditure. To further understand the cellular mechanisms by which glucagon and related ligands activate the glucagon receptor (GCGR), we investigate...

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Detalles Bibliográficos
Autores principales: Cegla, Jaimini, Jones, Ben J., Gardiner, James V., Hodson, David J., Marjot, Thomas, McGlone, Emma R., Tan, Tricia M., Bloom, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551549/
https://www.ncbi.nlm.nih.gov/pubmed/28586439
http://dx.doi.org/10.1210/en.2016-1755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551549/
https://www.ncbi.nlm.nih.gov/pubmed/28586439
http://dx.doi.org/10.1210/en.2016-1755

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