Cargando…
RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling
Endogenous satiety hormones provide an attractive target for obesity drugs. Glucagon causes weight loss by reducing food intake and increasing energy expenditure. To further understand the cellular mechanisms by which glucagon and related ligands activate the glucagon receptor (GCGR), we investigate...
Autores principales: | Cegla, Jaimini, Jones, Ben J., Gardiner, James V., Hodson, David J., Marjot, Thomas, McGlone, Emma R., Tan, Tricia M., Bloom, Stephen R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551549/ https://www.ncbi.nlm.nih.gov/pubmed/28586439 http://dx.doi.org/10.1210/en.2016-1755 |
Ejemplares similares
-
Receptor Activity-Modifying Protein 2 (RAMP2) alters glucagon receptor trafficking in hepatocytes with functional effects on receptor signalling
por: McGlone, Emma Rose, et al.
Publicado: (2021) -
Hepatocyte cholesterol content modulates glucagon receptor signalling
por: McGlone, Emma Rose, et al.
Publicado: (2022) -
Loading and Unloading Weaned Pigs: Effects of Bedding Types, Ramp Angle, and Bedding Moisture
por: Garcia, Arlene, et al.
Publicado: (2014) -
Loading and Unloading Finishing Pigs: Effects of Bedding Types, Ramp Angle, and Bedding Moisture
por: Garcia, Arlene, et al.
Publicado: (2014) -
The Effects of Using a Ramp and Elevator to Load and Unload Trailers on the Behavior and Physiology of Piglets
por: McGlone, John, et al.
Publicado: (2014)