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Role of ERα in Mediating Female Uterine Transcriptional Responses to IGF1

Estrogen (E2) signaling through its nuclear receptor, E2 receptor α (ERα) increases insulinlike growth factor 1 (IGF1) in the rodent uterus, which then initiates further signals via the IGF1 receptor. Directly administering IGF1 results in similar biological and transcriptional uterine responses. Ou...

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Detalles Bibliográficos
Autores principales: Hewitt, Sylvia C., Winuthayanon, Wipawee, Lierz, Sydney L., Hamilton, Katherine J., Donoghue, Lauren J., Ramsey, J. Tyler, Grimm, Sara A., Arao, Yukitomo, Korach, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551553/
https://www.ncbi.nlm.nih.gov/pubmed/28586424
http://dx.doi.org/10.1210/en.2017-00349