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Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation

Despite frequent herpes simplex virus (HSV) reactivation, peripheral nerve destruction and sensory anesthesia are rare. We discovered that skin biopsies obtained during asymptomatic human HSV-2 reactivation exhibit a higher density of nerve fibers relative to biopsies during virological and clinical...

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Detalles Bibliográficos
Autores principales: Peng, Tao, Chanthaphavong, R. Savanh, Sun, Sijie, Trigilio, James A., Phasouk, Khamsone, Jin, Lei, Layton, Erik D., Li, Alvason Z., Correnti, Colin E., De van der Schueren, Willem, Vazquez, Julio, O’Day, Diana R., Glass, Ian A., Knipe, David M., Wald, Anna, Corey, Lawrence, Zhu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551564/
https://www.ncbi.nlm.nih.gov/pubmed/28663436
http://dx.doi.org/10.1084/jem.20160581