Cargando…
Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation
Despite frequent herpes simplex virus (HSV) reactivation, peripheral nerve destruction and sensory anesthesia are rare. We discovered that skin biopsies obtained during asymptomatic human HSV-2 reactivation exhibit a higher density of nerve fibers relative to biopsies during virological and clinical...
Autores principales: | Peng, Tao, Chanthaphavong, R. Savanh, Sun, Sijie, Trigilio, James A., Phasouk, Khamsone, Jin, Lei, Layton, Erik D., Li, Alvason Z., Correnti, Colin E., De van der Schueren, Willem, Vazquez, Julio, O’Day, Diana R., Glass, Ian A., Knipe, David M., Wald, Anna, Corey, Lawrence, Zhu, Jia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551564/ https://www.ncbi.nlm.nih.gov/pubmed/28663436 http://dx.doi.org/10.1084/jem.20160581 |
Ejemplares similares
-
Tissue-Resident-Memory CD8(+) T Cells Bridge Innate Immune Responses in Neighboring Epithelial Cells to Control Human Genital Herpes
por: Peng, Tao, et al.
Publicado: (2021) -
Optimizing Deep Learning-Based Segmentation of Densely Packed Cells using Cell Surface Markers
por: Han, Sunwoo, et al.
Publicado: (2023) -
Immune Surveillance by CD8αα(+) Skin Resident T Cells in Human Herpesvirus Infection
por: Zhu, Jia, et al.
Publicado: (2013) -
Model of vaccine efficacy against HSV-2 superinfection of HSV-1 seropositive mice demonstrates protection by antibodies mediating cellular cytotoxicity
por: Burn Aschner, Clare, et al.
Publicado: (2020) -
Interleukin-1α released from HSV-1 infected keratinocytes acts as a functional alarmin in the skin
por: Milora, Katelynn A., et al.
Publicado: (2014)