NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity

Mitochondrial dysfunction is the most prominent source of oxidative stress in acute and chronic kidney disease. NLRX1 is a receptor of the innate immune system that is ubiquitously expressed and localized in mitochondria. We investigated whether NLRX1 may act at the interface of metabolism and innat...

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Detalles Bibliográficos
Autores principales: Stokman, Geurt, Kors, Lotte, Bakker, Pieter J., Rampanelli, Elena, Claessen, Nike, Teske, Gwendoline J.D., Butter, Loes, van Andel, Harmen, van den Bergh Weerman, Marius A., Larsen, Per W.B., Dessing, Mark C., Zuurbier, Coert J., Girardin, Stephen E., Florquin, Sandrine, Leemans, Jaklien C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551566/
https://www.ncbi.nlm.nih.gov/pubmed/28626071
http://dx.doi.org/10.1084/jem.20161031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551566/
https://www.ncbi.nlm.nih.gov/pubmed/28626071
http://dx.doi.org/10.1084/jem.20161031

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