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miR-99 regulates normal and malignant hematopoietic stem cell self-renewal

The microRNA-99 (miR-99) family comprises a group of broadly conserved microRNAs that are highly expressed in hematopoietic stem cells (HSCs) and acute myeloid leukemia stem cells (LSCs) compared with their differentiated progeny. Herein, we show that miR-99 regulates self-renewal in both HSCs and L...

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Detalles Bibliográficos
Autores principales: Khalaj, Mona, Woolthuis, Carolien M., Hu, Wenhuo, Durham, Benjamin H., Chu, S. Haihua, Qamar, Sarah, Armstrong, Scott A., Park, Christopher Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551568/
https://www.ncbi.nlm.nih.gov/pubmed/28733386
http://dx.doi.org/10.1084/jem.20161595