Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Immunotherapy using checkpoint-blocking antibodies against targets such as CTLA-4 and PD-1 can cure melanoma and non–small cell lung cancer in a subset of patients. The presence of CD8 T cells in the tumor correlates with improved survival. We show that immuno–positron emission tomography (immuno-PE...

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Detalles Bibliográficos
Autores principales: Rashidian, Mohammad, Ingram, Jessica R., Dougan, Michael, Dongre, Anushka, Whang, Katherine A., LeGall, Camille, Cragnolini, Juan J., Bierie, Brian, Gostissa, Monica, Gorman, James, Grotenbreg, Gijsbert M., Bhan, Atul, Weinberg, Robert A., Ploegh, Hidde L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551571/
https://www.ncbi.nlm.nih.gov/pubmed/28666979
http://dx.doi.org/10.1084/jem.20161950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551571/
https://www.ncbi.nlm.nih.gov/pubmed/28666979
http://dx.doi.org/10.1084/jem.20161950

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