Regulation of brain insulin signaling: A new function for tau

In this issue of JEM, Marciniak et al. (https://doi.org/10.1084/jem.20161731) identify a putative novel function of tau protein as a regulator of insulin signaling in the brain. They find that tau deletion impairs hippocampal response to insulin through IRS-1 and PTEN dysregulation and suggest that,...

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Detalles Bibliográficos
Autores principales: Gratuze, Maud, Planel, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551584/
https://www.ncbi.nlm.nih.gov/pubmed/28652305
http://dx.doi.org/10.1084/jem.20170979